In developed countries, most of the population recognizes that they are facing environmental and social threats which are mainly related to global warming.The problem associated with an ecological footprint, particularly water shortage, ecosystems, climate change, deforestation, and declining biodiversity, is considered a harmful threat to human li
The response regulator Skn7 of Aspergillus fumigatus is essential for the antifungal effect of fludioxonil
Abstract Aspergillus fumigatus is an important fungal pathogen that represents a major threat for severely immunocompromised patients.Cases of invasive aspergillosis are associated with a high mortality rate, which reflects the limited treatment options that are currently available.The development of novel therapeutic approaches is therefore an urg
A meta-analysis approach for characterizing pan-cancer mechanisms of drug sensitivity in cell lines.
Understanding the heterogeneous drug response of cancer patients is essential to precision oncology.Pioneering genomic analyses of individual cancer subtypes have begun to identify key determinants of resistance, including up-regulation of multi-drug resistance (MDR) genes and mutational alterations of drug targets.However, these alterations are su
Application of an Inverse Distance Weighted Anisotropic Method for Rock Quality Designation distribution in Eastern Kahang deposit, Central Iran
Estimation of Rock Quality Designation (RQD) Urinary Drainage Bags distribution with low value of error is crucial for mining excavation based on geomechanical data.This paper proposes an application of an Inverse Distance Weighted Anisotropic Method (IDWAM) based on combined variograms to construct RQD block model in Kahang Copper-Molybdenum (Cu-M